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Basic research using pluripotent stem cells and stem cell-based models in disease modeling, drug discovery, toxicology testing, regenerative medicine, and exciting new research areas like cultivated meat relies on antiquated manual cell culture techniques. We want to help.
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Stem cell expansion
Pluripotent stem cell expansion using either embryonic stem cells (ES) or induced pluripotent stem cells (iPSC) is a critical technique for producing cells used in disease modeling, drug discovery and therapeutic development. The expansion process involves the proliferation of ES/iPSCs to obtain sufficient quantities for research or translation to the clinic while maintaining the ES/iPSC’s pluripotency and differentiation capacity.
Cardiomyocyte differentiation
Emmet automatically scales and differentiates human iPS cells to Cardiomyocytes with a range of applications from basic research and development, drug testing and cellular therapeutics
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Emmet

Emmet is an intelligent machine that automates your TC flask cell culture workflows.

With a unified hardware and software stack in a single bench-top instrument, Emmet brings machine learning to the tissue culture lab.

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Emmet fits your needs

Standardize, streamline, and scale your cell culture workflows.

Reclaim your weekend

No more weekend work! What more could you want?

Reduce variability

Say goodbye to operator and batch-to-batch variability.

Elevate your science

Culture up to 18 T flasks in parallel.

Unlimited potential

Supports any media, coating, cell line and protocol.

Emmet standardises and automates the culture of any cell type.

Coating
Seeding
Feeding
Sampling
Passaging
Differentiation
Harvesting

Minimise setup time and contamination risks

1

Sterile enclosure:

Emmet is designed to operate outside of a Class II safety cabinet or TC hood with an aseptically closed fluid management system that enables automated sterile fluid transfer and minimises contamination risks.

2

‍Incubator:

Emmet's gas-controlled incubator has an adaptive process control system; you define optimal parameters (e.g., temperature, atmospheric CO₂), and Emmet maintains them to keep your cells healthy & happy.

3

Integrated Screen‍:

The integrated screen provides real-time monitoring of incubator CO2 and temperature levels, giving you complete confidence in your environment’s stability.

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4

Refrigerator:

Emmet's has an onboard refrigerator for reagent storage. It makes set-up a breeze (say goodbye to changing bags of media every day!) and mitigates thermocycling-related degradation of your non-thermal-stable factors and reagents.

Maximising productivity, minimising Interaction

1

Rocking platform & cell culture vessels:

Emmet's rocking platform enables homogenous fluid distribution across an entire flask. With room for up to 18 flasks of any size, you can bulk up a single cell line for banking or manufacture.

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2

‍Reagent storage:

Smart storage, uninterrupted workflows. Accommodates 7 fully connected reagent bottles across refrigerated and ambient zones, plus extra capacity for on-hand spares.

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3

Fluid management:

Say goodbye to managing endless tubes. Our patented cartridge-based fluidics system puts an entire fluid manifold in a machined block that fits in your hand, saving space.

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4

In-line analytics:

Command your workflow from anywhere. Our intuitive cloud-based platform empowers you to design custom protocols, track real-time machine progress, and monitor critical environmental metrics, giving you total laboratory control right at your fingertips.

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Stem cell expansion
Differentiations
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Stem cell expansion

Emmet standaridses and streamlines ES/iPSC expansion with fully automated media changes, passaging, and harvesting. Spend less time feeding and banking cells, and more time pushing the frontiers of scientific knowledge.

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Differentiations

Emmet standardises the differentiation protocols. Say goodbye to human error and tedious media exchanges and hello to 24/7 automation, enabling you to perform DOE style conditions testing and to develop robust, entirely novel protocols.

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Frequently asked questions

Here are some answers to the most common questions we get asked about Emmet.
What is Emmet, and what can it do?

Emmet is an intelligent machine designed to automate and scale mammalian cell culture workflows, specifically TC flask-based protocols.

Think of Emmet as an incubator, TC hood, refrigerator, process monitoring system, and cell culture technician, all in one machine (e.g., a unified hardware and software stack in a single instrument footprint).

Emmet standardises and automates cell culture workflows, including seeding, media exchange/perfusion, passaging, differentiation, and harvesting.

With Emmet, you can spend less time moving liquids between flasks and more time designing and analysing experiments (and enjoying your weekends!)

What cell types can Emmet culture?

Engineered for ultimate versatility. The platform offers seamless compatibility across any mammalian cell type, from sensitive human induced pluripotent stem cells (hiPSCs) and robust HEK lines to diverse cancer cell models and beyond.

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What cell culture vessels and cartridges does Emmet support?

Emmet is compatible with any commercially available tissue culture (TC) flask: T25, T75 & T225.

TC flasks can be plasma-treated (anchorage-dependent culture) or non-treated (suspension-adapted culture).

We are actively developing:

    1) Parallelised, closed fluidic cartridges to support adherent culture based scale up of autologous and allogeneic therapeutics.

    2) Dedicated suspension cell culture vessels for scale-down, multiplexed experiments.

Can I culture multiple cell lines in Emmet?

Our current platform is highly versatile for R&D environments, allowing you to culture different cell lines sequentially by utilising our automated wash protocol. While we do not guarantee total cross-contamination prevention for sensitive parallel workflows today, a next-generation architecture featuring multiple independent, closed-loop fluidics channels is already actively in development to unlock fully isolated multi-line processing.

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What is the fluidic management system, and how many inputs can it support?

Emmet utilises a specialised cartridge manifold for flexible, automated fluid management. By using pneumatic pressure to open and close internal membrane valves, the system effortlessly routes liquids from any point to point.

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Does Emmet have imaging capabilities?

Absolutely. Emmet features a sophisticated, fully integrated onboard imaging system paired with advanced software. You can remotely direct the microscope to target any specific flask for real-time viewing and crisp photo capture. Once captured, your high-resolution images are securely archived onboard, allowing you to seamlessly deploy our automated confluence analysis tools for precise, quantifiable growth metrics without ever disturbing your culture environment.

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What analytics systems does Emmet have?

The system features a comprehensive, multi-sensor analytical suite for real-time monitoring and environmental control:

o Integrated Climate Tracking: Real-time diagnostics for core incubation variables, including incubator temperature and CO2 levels.

o Dynamic Flow Analytics: Onboard pressure diagnostics that constantly regulate and maintain precise fluidic flow rates.

o Automated Growth Metrics: Integrated image-based analytics providing seamless, on-demand confluence analysis.

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How to you write and run protocols for Emmet?

Designing and executing your workflows is entirely seamless thanks to Emmet’s cloud platform. The platform features a dedicated protocol builder utilising an intuitive, visual drag-and-drop system. You can easily map out your entire experiment from a web browser, then securely send the protocol directly to the machine to begin your automated run.

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Can I monitor Emmet remotely?

Emmet’s secure cloud platform gives you total visibility into your laboratory, no matter where you are. From a remote browser, you can log in to check the exact progress of your active protocol, view real-time run data, and continuously track critical environmental metrics, ensuring complete confidence that your cultures are thriving 24/7.

Related resources

Automated hiPSC expansion: Emmet

Showcasing the efficacy of expanding hiPSCs from a T25 to a T225 in a closed, automated bench-top system (Emmet).
App Notes
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1.17.2025
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Research scientist

Accelerate discovery
How We Can Help

Laboratory manager

Enhance lab efficiency
How We Can Help

Lab automation lead

Automation that works
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